Litcius/Paper detail

Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment

Галина Ф. Махаева, Sofya V. Lushchekina, N. V. Kovaleva, T. Yu. Astakhova, Natalia P. Boltneva, Елена В. Рудакова, Olga G. Serebryakova, Alexey N. Proshin, И. В. Серков, Т. П. Трофимова, В. А. Тафеенко, Eugene V. Radchenko, Vladimir A. Palyulin, Владимир Петрович Фисенко, Jan Korábečný, Ondřej Soukup, Rudy J. Richardson

2021Bioorganic Chemistry49 citationsDOI

Topics & Concepts

ButyrylcholinesteraseChemistryAcetylcholinesterasePiperazineAchéStereochemistryLead compoundCholinesteraseEnzymeBiochemistryPharmacologyIn vitroOrganic chemistryMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity