Design, synthesis and biological evaluation of novel carbohydrate-based sulfonamide derivatives as antitumor agents
Shuang Hao, Xue Cheng, Xin Wang, Ran An, Hang Xu, Mengbi Guo, Chuanchao Li, Yitong Wang, Zhuang Hou, Chun Guo
Topics & Concepts
ChemistryCarbonic anhydraseSulfonamideAcetazolamideIC50Docking (animal)StereochemistryLinkerMoietyPharmacophoreCombinatorial chemistryIn vitroEnzymeBiochemistryNursingAnesthesiaOperating systemComputer scienceMedicineEnzyme function and inhibitionSynthesis and Catalytic ReactionsSynthesis and Biological Evaluation