Bone marrow mesenchymal stem cells-derived exosomes containing miR-539-5p inhibit pyroptosis through NLRP3/caspase-1 signalling to alleviate inflammatory bowel disease
Dandan Wang, Hui Xue, Jianfeng Tan, Penglin Liu, Cuixia Qiao, Chengjian Pang, Lize Zhang
Topics & Concepts
PyroptosisProinflammatory cytokineMesenchymal stem cellExosomeChemistryMicrovesiclesImmunologyCell biologyMolecular biologyInflammasomeInflammationmicroRNAMedicineBiologyBiochemistryGeneInflammasome and immune disordersInflammation biomarkers and pathwaysExtracellular vesicles in disease