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Myelin Oligodendrocyte Glycoprotein (MOG) antibody-associated meningoencephalitis due to Mycoplasma pneumoniae infection

Xiang-Dong Zeng, Hui Chen, Wen-Guang Hu

2022Neurological Research9 citationsDOI

Abstract

Although myelin oligodendrocyte glycoprotein (MOG) antibody-associated disorders include a wide spectrum of syndromes, manifestations with meningoencephalitis symptoms due to M. pneumoniae infection were quite infrequent. We admitted an 8-years-old girl who presented with recurrent fever accompanied by headache and mild cough, her Cerebral spinal fluid polynucleated cells was elevated and progressively higher, her cranial MRI showed meningeal enhancement initially and multiple intracranial lesions later, serum M. pneumoniae-IgM and MOG-IgG were positive, she was diagnosed with MOG-IgG associated meningoencephalitis due to M. pneumoniae infection, the treatment consisted of intravenous immunoglobulin, glucocorticoid, and erythromycin, then she was completely recovered.

Topics & Concepts

Mycoplasma pneumoniaeMeningoencephalitisMyelin oligodendrocyte glycoproteinMedicineImmunologyAntibodyCerebrospinal fluidEncephalitisImmunoglobulin MPathologyPneumoniaImmunoglobulin GInternal medicineMultiple sclerosisVirusExperimental autoimmune encephalomyelitisAutoimmune Neurological Disorders and TreatmentsPolyomavirus and related diseasesBacterial Infections and Vaccines
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