Oxidative stress and the cardiovascular effects of air pollution
Mark R. Miller
Abstract
Cardiovascular causes have been estimated to be responsible for more than two thirds of the considerable mortality attributed to air pollution. There is now a substantial body of research demonstrating that exposure to air pollution has many detrimental effects throughout the cardiovascular system. Multiple biological mechanisms are responsible, however, oxidative stress is a prominent observation at many levels of the cardiovascular impairment induced by pollutant exposure. This review provides an overview of the evidence that oxidative stress is a key pathway for the different cardiovascular actions of air pollution.
Topics & Concepts
Oxidative stressAir pollutionCardiovascular healthAir pollutantsPollutantPollutionEnvironmental healthOxidative damageMedicineEnvironmental scienceBiologyInternal medicineDiseaseEcologyAir Quality and Health ImpactsClimate Change and Health ImpactsAir Quality Monitoring and Forecasting