Silibinin alleviates ferroptosis of rat islet β cell INS-1 induced by the treatment with palmitic acid and high glucose through enhancing PINK1/parkin-mediated mitophagy
Qingqing Du, Xiaoyun Wu, Kai Ma, Weiwei Liu, Panwen Liu, Toshihiko Hayashi, Kazunori Mizuno, Shunji Hattori, Hitomi Fujisaki, Takashi Ikejima
Topics & Concepts
MitophagyChemistryMitochondrionPINK1SilibininAutophagyGLUT4BiochemistryCell biologyBiologyPharmacologyApoptosisChromosomal translocationGeneFerroptosis and cancer prognosisAutophagy in Disease and TherapyMetabolism, Diabetes, and Cancer