Catalytic Strategies for the Asymmetric Construction of Cyclic Frameworks with a Halogenated Tetrasubstituted Stereocenter
Yue Liu, Hai‐Jun Leng, Qing‐Zhu Li, Jun‐Long Li
Abstract
Abstract The efficient and enantioselective construction of cyclic compounds with a halogenated tetrasubstituted carbon through various catalytic strategies remains challenging. Thus, research on modern asymmetric catalysis is important. In this review, recent achievements that streamlined the synthesis of halogenated cyclic molecules through organocatalysis or transition‐metal catalysis were introduced. magnified image
Topics & Concepts
StereocenterEnantioselective synthesisChemistryCatalysisOrganocatalysisCombinatorial chemistryOrganic chemistryAsymmetric Synthesis and CatalysisCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis