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Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation

Menghua Zhou, Bingjie Guan, Youdong Liu, Qi Gu, W.T. Chen, Bowen Xie, Mantang Zhou, Jianjun Xiang, Senlin Zhao, Qian Zhao, Dongwang Yan, Dongwang Yan

2025Cancer Letters24 citationsDOI

Topics & Concepts

Extracellular vesiclesTumor microenvironmentExtracellularMicrovesiclesNeutrophil extracellular trapsExtracellular matrixMacrophageImmunologyBiologyCancer researchCell biologyChemistryImmune systemInflammationIn vitroBiochemistryGenemicroRNAExtracellular vesicles in diseaseImmune cells in cancerPhagocytosis and Immune Regulation
Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation | Litcius