Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing
Grace E. McAuley, Gloria Yiu, Patrick Chang, Gregory A. Newby, Beatriz Campo-Fernández, Sorel Fitz‐Gibbon, Wu Xiaomeng, Sung‐Hae Kang, Amber Garibay, Jeffrey Butler, Valentina Christian, Ryan L. Wong, Kelcee A. Everette, Anthony Azzun, Hila Gelfer, Christopher S. Seet, Aru Narendran, Luis Murguía-Favela, Zulema Romero, Nicola Wright, David R. Liu, Gay M. Crooks, Donald B. Kohn
Topics & Concepts
BiologyHuman immunodeficiency virus (HIV)Base (topology)VirologyCD3Severe combined immunodeficiencyImmunodeficiencyCell biologyGeneticsComputational biologyImmunologyGeneImmune systemCD8MathematicsMathematical analysisCAR-T cell therapy researchCRISPR and Genetic EngineeringCytomegalovirus and herpesvirus research