Litcius/Paper detail

Efficient 3D imaging and pathological analysis of the human lymphoma tumor microenvironment using light-sheet immunofluorescence microscopy

Liting Chen, Meng Jiao, Yao Zhou, Fang Zhao, Yifan Ma, Wenyang Feng, Xingyu Chen, Jin Jin, Shimeng Gao, Jianchao Liu, Man Zhang, Aichun Liu, Zhenya Hong, Tang Jiang, Dong Kuang, Liang Huang, Yicheng Zhang, Peng Fei

2023Theranostics9 citationsDOIOpen Access PDF

Abstract

We present an advanced imaging-based method for efficient 3D visualization and high-content cellular analysis of the lymphoma TME, rendering it a valuable tool for tumor pathological diagnosis and other clinical research.

Topics & Concepts

LymphomaPathologyTumor microenvironmentColocalizationLight sheet fluorescence microscopyCancer researchMedicineBiologyMicroscopyCell biologyTumor cellsScanning confocal electron microscopyAdvanced Fluorescence Microscopy TechniquesCAR-T cell therapy researchImmunotherapy and Immune Responses