Co-delivery of simvastatin and demineralized bone matrix hierarchically from nanosheet-based supramolecular hydrogels for osteogenesis
Xiao Zhang, Jiabing Fan, Chen Chen, Tara Aghaloo, Min Lee
Abstract
. This work provides the first demonstration of molecular and supramolecular engineering of hydrogels to load osteoinductive agents hierarchically for bone regeneration, contributing to the development of a brand-new strategy for dealing with compatibility between scaffolds and osteogenic agents.
Topics & Concepts
Self-healing hydrogelsMaterials scienceSimvastatinSupramolecular chemistryNanosheetBiomedical engineeringMatrix (chemical analysis)NanotechnologyComposite materialPolymer chemistryChemistryEngineeringMoleculeOrganic chemistryMedicineInternal medicineSupramolecular Self-Assembly in MaterialsBone Tissue Engineering MaterialsBone and Dental Protein Studies