ATP regeneration by a single polyphosphate kinase powers multigram-scale aldehyde synthesis<i>in vitro</i>
Michele Tavanti, Joseph Hosford, Richard C. Lloyd, Murray J. B. Brown
Abstract
Towards scalable ATP recycling: a newly identified PPK2-III biocatalyst unlocked fully<italic>in vitro</italic>multigram-scale aldehyde synthesis employing a carboxylic acid reductase.
Topics & Concepts
AldehydeAldehyde ReductaseIn vitroPolyphosphateChemistryBiocatalysisKinaseCombinatorial chemistryEnzymeBiochemistryOrganic chemistryReductaseCatalysisReaction mechanismPhosphateCoagulation, Bradykinin, Polyphosphates, and AngioedemaEnzyme Catalysis and ImmobilizationPeptidase Inhibition and Analysis