Views on the uses of comprehensive two-dimensional gas chromatography-mass spectrometry in food analysis over the literature period 2018–2023
Peter Q. Tranchida, Mariosimone Zoccali, Luigi Mondello
Abstract
The present manuscript contains critical and constructive views on the uses of comprehensive two-dimensional gas chromatography-mass spectrometry (GC × GC-MS) within the context of food analysis. Focus is devoted to the GC × GC-MS literature covering the period 2018–2023 (nearly 170 articles), even though the conclusions made can be applied, to some extent, to general ones. In fact, even though the use of GC × GC in food analysis has a publication history of just over two decades, it has never gained a firm hold in this field of application, in neither the industry nor in academia. Possible reasons for this lack, along with analytical challenges for which specific GC × GC-MS configurations would certainly be useful, are herein given.