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Apple polyphenol phloretin complexed with ruthenium is capable of reprogramming the breast cancer microenvironment through modulation of PI3K/Akt/mTOR/VEGF pathways

Souvik Roy, Anil K. Mondru, Tania Chakraborty, Abhijit Das, Sandipan Dasgupta

2021Toxicology and Applied Pharmacology30 citationsDOI

Topics & Concepts

PhloretinPI3K/AKT/mTOR pathwayCancer researchChemistryApoptosisRutheniumProtein kinase BCell biologyBiologyBiochemistryCatalysisMetal complexes synthesis and propertiesCancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer
Apple polyphenol phloretin complexed with ruthenium is capable of reprogramming the breast cancer microenvironment through modulation of PI3K/Akt/mTOR/VEGF pathways | Litcius