Gut microbiota alteration and modulation in hepatitis B virus-related fibrosis and complications: Molecular mechanisms and therapeutic inventions
Yaoguang Li, Zu‐Jiang Yu, Ang Li, Zhigang Ren
Abstract
antiviral treatment, the gut microbiota dysfunction tends to be improved. Conversely, the recovery of gut microbiota can promote the regression of liver fibrosis. Therapeutic strategies targeted on gut microbiota (rifaximin, probiotics, engineered probiotics and fecal microbiota transplantation) have been applied to animal models and patients, obtaining satisfactory results.
Topics & Concepts
Gut floraCirrhosisImmunologyRifaximinHepatitis B virusSpontaneous bacterial peritonitisLiver diseaseHepatic encephalopathyHepatocellular carcinomaFibrosisMedicineBiologyVirusGastroenterologyInternal medicineMicrobiologyAntibioticsHepatitis B Virus StudiesLiver Disease Diagnosis and TreatmentGut microbiota and health