Microbial and genetic-based framework identifies drug targets in inflammatory bowel disease
Zhihan Wang, Kai Guo, Pan Gao, Qinqin Pu, Ping Lin, Shugang Qin, Na Xie, Junguk Hur, Changlong Li, Canhua Huang, Min Wu
Abstract
validation, we built a framework for predicting biomarkers and host-microbe interaction targets and identifying repurposing drugs for IBD, which may be tested further for clinical application. This approach may also be a tool for repurposing drugs for treating other diseases.
Topics & Concepts
Inflammatory bowel diseaseDiseaseDrugDrug responseComputational biologyPharmacogenomicsDrug developmentMedicineBiologyBioinformaticsPharmacologyPathologyInflammatory Bowel DiseaseGut microbiota and healthHelicobacter pylori-related gastroenterology studies