Hydrogen sulfide sensing using an aurone-based fluorescent probe
Arjun Kafle, Shrijana Bhattarai, Justin M. Miller, Scott T. Handy
Abstract
)-one (6g) utilizing a low molecular weight aurone fluorophore. During these studies, the modular nature of the synthesis was used to quickly overcome problems with solubility, overlap of excitation of the probe and reduced product, and rate of reaction, resulting in a final compound that is efficient and sensitive for the detection of hydrogen sulfide. The limitation of slow reaction and the reduced fluorescence in a biologically relevent medium was solved by employing cationic surfactant cetyltrimethyl ammonium bromide (CTAB). The probe features a high fluorescence enhancement, fast response (10-30 min), and good sensitivity (1 μm) and selectivity for hydrogen sulfide.
Topics & Concepts
Hydrogen sulfideFluorescenceChemistrySulfidePhotochemistryInorganic chemistryCombinatorial chemistryOrganic chemistrySulfurOpticsPhysicsMolecular Sensors and Ion DetectionSulfur Compounds in BiologyLuminescence and Fluorescent Materials