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Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation

Xue-Ming LI, Ding-Yi YUAN, Ya-Hui LIU, Lei ZHU, Hong-Kun QIN, Yu-Bing YANG, Yan LI, Fang YAN, Ya-Jing WANG

2022Chinese Journal of Natural Medicines17 citationsDOI

Topics & Concepts

Panax notoginsengColorectal cancerImmune systemImmunosuppressionSTAT proteinMedicineCancer researchTumor microenvironmentActivator (genetics)CancerPharmacologyColitisImmunologyTransactivationInflammatory bowel diseaseLipopolysaccharideMouse model of colorectal and intestinal cancerInflammationMechanism of actionDownregulation and upregulationImmune toleranceApoptosisGinseng Biological Effects and ApplicationsTryptophan and brain disordersGut microbiota and health
Panax notoginseng saponins prevent colitis-associated colorectal cancer via inhibition IDO1 mediated immune regulation | Litcius