Palladium catalyzed decarboxylative β-<i>C</i>-glycosylation of glycals with oxazol-5-(4<i>H</i>)-ones as acceptors
Wei‐Yi Ding, Huanhuan Liu, Jun Kee Cheng, Hui Yao, Shao‐Hua Xiang, Bin Tan
Abstract
Palladium catalyzed decarboxylative glycosylation of bicyclic glycals affords a series of C -glycosylated oxazol-5-(4 H )-ones with high efficiency and exquisite chemo- and stereoselectivity at the anomeric center under mild reaction conditions.
Topics & Concepts
ChemistryPalladiumGlycosylationStereoselectivityCatalysisAnomerBicyclic moleculeOrganic chemistryStereochemistryCombinatorial chemistryBiochemistryCarbohydrate Chemistry and SynthesisChemical Synthesis and AnalysisGlycosylation and Glycoproteins Research