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PD-L1 induces macrophage polarization toward the M2 phenotype via Erk/Akt/mTOR

Wei Yi, Mengjun Liang, Liping Xiong, Ning Su, Xiang Gao, Zongpei Jiang

2021Experimental Cell Research72 citationsDOI

Topics & Concepts

Macrophage polarizationBiologyDownregulation and upregulationPI3K/AKT/mTOR pathwayCell biologyProtein kinase BMAPK/ERK pathwayLY294002PD-L1Cancer researchSignal transductionImmune systemMacrophageImmunologyGeneBiochemistryIn vitroImmunotherapyImmune cells in cancerEpigenetics and DNA MethylationCancer Immunotherapy and Biomarkers
PD-L1 induces macrophage polarization toward the M2 phenotype via Erk/Akt/mTOR | Litcius