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Explainability in the age of large language models for healthcare

Munib Mesinovic, Peter Watkinson, Tingting Zhu

2025Communications Engineering25 citationsDOIOpen Access PDF

Abstract

Large language models show remarkable potential in healthcare but face critical explainability challenges that must be addressed before widespread clinical deployment. Here, we examine technical and regulatory solutions needed to develop trustworthy, transparent large language models for responsible healthcare integration. Large language models show remarkable potential in healthcare but face critical explainability challenges that must be addressed before widespread clinical deployment. Here, Munib Mesinovic, Peter Watkinson and Tingting Zhu examine technical and regulatory solutions needed to develop trustworthy, transparent large language models for responsible healthcare integration.

Topics & Concepts

Health carePsychologyComputer scienceLinguisticsEconomicsPhilosophyEconomic growthArtificial Intelligence in Healthcare and EducationMachine Learning in HealthcareExplainable Artificial Intelligence (XAI)