Diabetes Mellitus and Oral Cancer: A Retrospective Study from Austria
Bernhard Remschmidt, Mauro Pau, Jan Gaessler, Wolfgang Zemann, Norbert Jakse, Michael Payer, Dániel Végh
Abstract
AIM: This study aimed to analyse the possible linkage between diabetes mellitus (DM) and oral cancer among Austrians. PATIENTS AND METHODS: We performed a retrospective DM and/or impaired fasting glucose (IFG) screening in 573 patients who underwent maxillofacial surgery under general anaesthesia between January 1, 2018 and December 31, 2019. RESULTS: Of the total patients, 26.5% (n=152) had cancer diagnosis, whereas the remaining 73.5% (n=421) formed the control group. The prevalence of glucose metabolism disorder (GMD) was significantly (p<0.00001) more common among cancer patients (59.9% vs. 36.5%). Squamous cell carcinoma and sublingual tumours represented the most common tumour type (93.4%) and location (35.5%), respectively. Smoking was significantly (p=0.00093) more common within the cancer group. CONCLUSION: Our data suggest an association between GMD and oral cancer.