Targeted exosomes for co-delivery of siFGL1 and siTGF-β1 trigger combined cancer immunotherapy by remodeling immunosuppressive tumor microenvironment
Xing Pei, Xiaojuan Zhang, Lu Zhang, Mengmeng Yuan, Lu Sun, Fei Yu, Bangmao Wang, Jingwen Zhao, Huining He, Victor C. Yang
Topics & Concepts
Tumor microenvironmentImmunotherapyImmune systemCancer researchCancer immunotherapyExosomeImmune checkpointMedicineMicrovesiclesImmunologyBiologyGenemicroRNABiochemistryExtracellular vesicles in diseaseImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers