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Polyhexamethylene guanidine phosphate induces pyroptosis via reactive oxygen species-regulated mitochondrial dysfunction in bronchial epithelial cells

Jun Young Park, Ji-Hee Kim, Chan Ho Park, Sung‐Hwan Kim, In-Hyeon Kim, Won Gil Cho

2024Toxicology13 citationsDOI

Topics & Concepts

PyroptosisReactive oxygen speciesProgrammed cell deathOxidative stressMitochondrial ROSMitochondrionCell biologyApoptosisChemistryCaspase 1Viability assayInflammationCaspaseBiologyImmunologyBiochemistryInflammasome and immune disordersInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Polyhexamethylene guanidine phosphate induces pyroptosis via reactive oxygen species-regulated mitochondrial dysfunction in bronchial epithelial cells | Litcius