Controlling placental spheroid growth and phenotype using engineered synthetic hydrogel matrices
Emily M. Slaby, Seema B. Plaisier, Sarah R. Brady, Shivani C. Hiremath, Jessica D. Weaver
Abstract
The human placenta is a complex organ comprised of multiple trophoblast subtypes, and inadequate models to study the human placenta in vitro limit the current understanding of human placental behavior and development.
Topics & Concepts
TrophoblastPlacentaSpheroidHuman placentaPhenotypeCell biologyIn vitroBiologyChemistryFetusPregnancyBiochemistryGeneticsGenePregnancy and preeclampsia studiesRenal and related cancersReproductive System and Pregnancy