Isolation and quantification of extracellular vesicle-encapsulated microRNA on an integrated microfluidic platform
Chia-Yu Sung, Chi-Chien Huang, Yi-Sin Chen, Keng‐Fu Hsu, Gwo‐Bin Lee
Abstract
dPCR) was found to be <12%. Additionally, spiked samples and clinical samples were used to test the performance of the developed platform. It is envisioned that the developed system can serve as a valuable and promising tool for OvCa biomarker measurements.
Topics & Concepts
Digital polymerase chain reactionmicroRNAMicrovesiclesLiquid biopsyBiomarkerExtracellular vesicleExtracellular vesiclesCancer biomarkersComputational biologyPolymerase chain reactionBiologyCancerMedicineCell biologyGeneInternal medicineBiochemistryExtracellular vesicles in diseaseMicroRNA in disease regulationAdvanced biosensing and bioanalysis techniques