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Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer

Jared Liu, Hsin-Wen Chang, Zhiming Huang, Mio Nakamura, Sahil Sekhon, Richard Ahn, Priscila Muñoz-Sandoval, Shrishti Bhattarai, Kristen M. Beck, Isabelle M. Sanchez, Eric Yang, Mariela Pauli, Sarah T. Arron, Wai‐Ping Fung‐Leung, Ernesto Muñoz, Xuejun Liu, Tina Bhutani, Jeffrey P. North, Anne M. Fourie, Michael D. Rosenblum, Wilson Liao

2020Journal of Allergy and Clinical Immunology143 citationsDOIOpen Access PDF

Topics & Concepts

AutoimmunityBiologyCD8ImmunologyRNAPsoriasisVirologyImmune systemGeneGeneticsT-cell and B-cell ImmunologyPsoriasis: Treatment and PathogenesisSingle-cell and spatial transcriptomics
Single-cell RNA sequencing of psoriatic skin identifies pathogenic Tc17 cell subsets and reveals distinctions between CD8+ T cells in autoimmunity and cancer | Litcius