Design, synthesis and bioactivity study of evodiamine derivatives as multifunctional agents for the treatment of hepatocellular carcinoma
Xiaohong Fan, Jiedan Deng, Tao Shi, Huaixiu Wen, Junfang Li, Ziyi Liang, Lei Fang, Dan Liu, Honghua Zhang, Yan Liang, Xiangyong Hao, Zhen Wang
Topics & Concepts
EvodiamineIn vivoHepatocellular carcinomaCancer researchChemistryApoptosisStromal cellCell cultureIn vitroCytotoxicityCancer cellPharmacologyCancerMedicineInternal medicineBiologyBiochemistryGeneticsBiotechnologyCancer therapeutics and mechanismsQuinazolinone synthesis and applicationsSynthesis and biological activity