Abnormalities of the type I interferon signaling pathway in lupus autoimmunity
Stefania Gallucci, Sowmya Meka, Ana M. Gamero
Topics & Concepts
BiologyImmunologyAutoimmunitySTAT1EpigeneticsInterferonInterferon type ISignal transductionIRF5ChromatinSTAT2IRF7Immune systemTranscription factorEpigenomeHistoneInterferon regulatory factorsDNA methylationGeneticsGeneInnate immune systemstatGene expressionSTAT3Systemic Lupus Erythematosus ResearchCytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology