Stereoselective synthetic strategies of stereogenic carbon centers featuring a difluoromethyl group
Fengyun Gao, Boyu Li, Yalan Wang, Qushuo Chen, Yongzhen Li, Kairong Wang, Wenjin Yan
Abstract
The scope of this review is to summarize routine asymmetric synthetic methods which enable the effective and selective introduction of difluoromethyl groups into the desired compounds, providing a general introduction to this important research area.
Topics & Concepts
StereocenterChemistryScope (computer science)StereoselectivityGroup (periodic table)Combinatorial chemistryOrganic chemistryEnantioselective synthesisComputer scienceCatalysisProgramming languageFluorine in Organic ChemistryAsymmetric Synthesis and CatalysisChemical Synthesis and Analysis