Highly efficient synthesis of C3-heteroaryl 3-fluorooxindoles <i>via</i> a one-pot stepwise Ce(<scp>iii</scp>)/photoassisted cross-dehydrogenative coupling/fluorooxidation process
Letian Zhang, Jiajun He, Jiabin Shen, Hao Xu, Dancheng Zhu, Chao Shen
Abstract
A one-pot stepwise strategy has been developed to afford C3-heteroaryl 3-fluorooxindoles via a Ce( iii )/photoassisted cross-dehydrogenative coupling/fluorooxidation process in moderate-to-good yields with excellent functional group compatibility.
Topics & Concepts
ChemistryCompatibility (geochemistry)Combinatorial chemistryMedicinal chemistryChemical engineeringEngineeringFluorine in Organic ChemistryCatalytic C–H Functionalization MethodsRadical Photochemical Reactions