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PROTAC targeted protein degraders: the past is prologue

Miklós Békés, David R. Langley, Craig M. Crews

2022Nature Reviews Drug Discovery3,053 citationsDOIOpen Access PDF

Topics & Concepts

UbiquitinProteasomeProtein degradationComputational biologyDrug discoveryNeddylationMedicineBioinformaticsBiologyUbiquitin ligaseGeneticsBiochemistryGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
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