Lipopolysaccharide-induced depression is associated with estrogen receptor-α/SIRT1/NF-κB signaling pathway in old female mice
Xi Jiang, Ziwei Chen, Xuefeng Yu, Jin Chen, Chonglu Sun, Changfeng Jing, Lexing Xu, Fuhe Liu, Wen-Juan Ni, Lei Chen
Topics & Concepts
EndocrinologyInternal medicineLipopolysaccharideTail suspension testBehavioural despair testEstrogen receptorTumor necrosis factor alphaCytokineStimulationEstrogenNF-κBInterleukinReceptorInterleukin 6Signal transductionHippocampusBiologyMedicineInflammationCell biologyCancerAntidepressantBreast cancerTryptophan and brain disordersStress Responses and CortisolMenopause: Health Impacts and Treatments