Porphyrin photosensitizer molecules as effective medicine candidates for photodynamic therapy: electronic structure information aided design
Wei-Huang Yin, Pengyuan Li, Hou-Hou Huang, Feng Lu, Shu‐Hui Liu, Xin Liu, Fu‐Quan Bai
Abstract
-porphyrin-PDI, Zn-porphyrin-PDI, Mg-porphyrin-PDI, Zn-porphyrin combined with PDI through single bond (compound 1), and two acetylenic bonds (compound 2) in this work would be proposed as potential PS candidates for PDT process. This study was expected to provide PS candidates for the development of novel medicines in PDT.
Topics & Concepts
PhotosensitizerPorphyrinPhotodynamic therapyMoleculePhotochemistryChemistryOrganic chemistryPhotodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsPorphyrin and Phthalocyanine Chemistry