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Impact of Smoking on Human Natural Killer Cell Activity: A Large Cohort Study

Yoon Suk Jung, Jung Ho Park, Dong Il Park, Chong Il Sohn, Jae Myun Lee, Tae Il Kim

2020Journal of Cancer Prevention24 citationsDOIOpen Access PDF

Abstract

< 0.001). NK cell activity was lower in current smokers. It also decreased with an increase in the number of cigarettes smoked, and it was negatively correlated with cotinine levels among current smokers. Our findings indicate a clear relationship between smoking and decreased NK cell activity.

Topics & Concepts

CotinineMedicineAsymptomaticNatural killer cellPopulationQuartileInternal medicineGastroenterologyImmunologyNicotineChemistryCytotoxic T cellBiochemistryEnvironmental healthIn vitroConfidence intervalImmune Cell Function and Interaction