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Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain

Lekha Mikkilineni, Danielle Natrakul, Norris Lam, Elisabet E. Manasanch, Jennifer Mann, Katherine A. Weissler, Nathan Wong, Jennifer N. Brudno, Stephanie L. Goff, James C. Yang, Micaela Ganaden, Rashmika Patel, Zhili Zheng, Jared J. Gartner, Kathryn R. Martin, Hao‐Wei Wang, Constance M. Yuan, Tyler Lowe, Irina Marić, Lipei Shao, Ping Jin, David F. Stroncek, Steven L. Highfill, Steven A. Rosenberg, James N. Kochenderfer

2023Molecular Therapy15 citationsDOIOpen Access PDF

Topics & Concepts

Multiple myelomaImmunoglobulin light chainAntigenChimeric antigen receptorHeavy chainChemistryImmunoglobulin heavy chainMolecular biologyCancer researchAntibodyBiologyImmunologyGeneBiochemistryT cellImmune systemCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology
Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain | Litcius