1,8-naphthalimide-based DNA intercalators and anticancer agents: a systematic review
Aeyaz Ahmad Bhat, Amel Gacem, Maytham T. Qasim, Nuha Almulla, Khursheed Muzammil, Manar G. Shalabi
Topics & Concepts
Rational designChemistryTopoisomeraseCombinatorial chemistryIntercalation (chemistry)BifunctionalAnticancer drugCamptothecinDNACytotoxicityTopoisomerase inhibitorComputational biologyDrugStereochemistryNanotechnologyBiochemistryBiologyPharmacologyMaterials scienceOrganic chemistryIn vitroCatalysisCancer therapeutics and mechanismsSynthesis and Biological EvaluationDNA and Nucleic Acid Chemistry