Synthesis, molecular modeling, and anticancer activity of new thiophene and thiophene-pyrazole analogues incorporating benzene-sulfonamide moiety as carbonic anhydrase isozymes (CA-IX and CA-XII)
Adel I. Alalawy, Kahdr Alatawi, Noof A. Alenazi, Ahmad Fawzi Qarah, Omar M. Alatawi, Rua B. Alnoman, Arwa Alharbi, Nashwa M. El-Metwaly
Topics & Concepts
ChemistryThiophenePyrazoleCarbonic anhydraseSulfonamideStereochemistryMoietySubstituentEnzymeOrganic chemistryEnzyme function and inhibitionSynthesis and Catalytic ReactionsChemical Reactions and Mechanisms