New chalcone-tethered 1,3,5-triazines potentiate the anticancer effect of cisplatin against human lung adenocarcinoma A549 cells by enhancing DNA damage and cell apoptosis
Marwa H. El‐Wakil, Sherine N. Khattab, Amira F. El‐Yazbi, Nefertiti El-Nikhely, Ahmed Soffar, Hosam H. Khalil
Topics & Concepts
CisplatinChemistryPropidium iodideApoptosisAnnexinMTT assayA549 cellDNA damageMolecular biologyCancer researchChalconeDNABiochemistryStereochemistryProgrammed cell deathBiologyChemotherapyGeneticsSynthesis and Characterization of Heterocyclic CompoundsDNA and Nucleic Acid ChemistryMetal complexes synthesis and properties