Intracellular Ca2+ dynamics in the ALA neuron reflect sleep pressure and regulate sleep in Caenorhabditis elegans
Shinichi Miyazaki, Taizo Kawano, Masashi Yanagisawa, Yu Hayashi
Abstract
and abolished the homeostatic regulation of sleep bouts. These findings indicate that ALA encodes sleep pressure and contributes to sleep homeostasis.
Topics & Concepts
Caenorhabditis elegansSleep (system call)IntracellularHomeostasisNeuroscienceBiologyOptogeneticsSleep deprivationCell biologyEndocrinologyCircadian rhythmGeneticsGeneComputer scienceOperating systemGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninSpaceflight effects on biology