Litcius/Paper detail

KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy

Jiacheng Guo, Li Ni, Qiuli Liu, Zongyao Hao, Guanghui Zhu, Xuege Wang, Hanling Wang, Qiang Pan‐Hammarström, Bin Xu, Ying Han, Guoying Zhang, Yannan Lian, Wei Zhang, Yongqiang Gu, Naiheng Lin, Xin Zeng, Zige Jin, Weihua Lan, Jun Jiang, Dong Gao, Liang Dong, Huairui Yuan, Chaozhao Liang, Jun Qin

2025Cancer Cell19 citationsDOI

Topics & Concepts

Cancer researchTransdifferentiationBiologyAndrogen receptorTransactivationProstate cancerPalmitoylationEpigeneticsCancerCell biologyGeneticsGene expressionStem cellGeneBiochemistryEnzymeCysteineProstate Cancer Treatment and ResearchCancer, Lipids, and MetabolismUbiquitin and proteasome pathways
KMT2C deficiency drives transdifferentiation of double-negative prostate cancer and confer resistance to AR-targeted therapy | Litcius