Ultra-sensitive biosensor based on CRISPR-Cas12a and Endo IV coupled DNA hybridization reaction for uracil DNA glycosylase detection and intracellular imaging
Kejun Dong, Wan Shu, Jiarui Zhang, Shuangshuang Cheng, Jun Zhang, Rong Zhao, Hua Teng, Wei Zhang, Hongbo Wang, Wei Zhang, Hongbo Wang
Topics & Concepts
CRISPRBiosensorDNA glycosylaseDNAUracil-DNA glycosylaseDetection limitChemistryComputational biologyBiologyBiochemistryDNA repairGeneChromatographyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesCytomegalovirus and herpesvirus research