Indoxyl sulfate induces ROS production via the aryl hydrocarbon receptor-NADPH oxidase pathway and inactivates NO in vascular tissues
Keisuke Nakagawa, Mayuko Itoya, Nao Takemoto, Yuika Matsuura, Masashi Tawa, Yasuo Matsumura, Mamoru Ohkita
Topics & Concepts
ApocyninNADPH oxidaseSuperoxideNitric oxideChemistryAscorbic acidAryl hydrocarbon receptorPharmacologyReactive oxygen speciesBiochemistryVascular smooth muscleOxidase testSodium nitroprussideEndotheliumEndocrinologyEnzymeBiologyOrganic chemistrySmooth muscleGeneFood scienceTranscription factorNitric Oxide and Endothelin EffectsDialysis and Renal Disease ManagementNeutrophil, Myeloperoxidase and Oxidative Mechanisms