Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development
Andrew Harvey, Renélyn A. Wolters, Raymond N. Deepe, Hannah G. Tarolli, Jenna R. Drummond, Allison M. Trouten, Auva Zandi, Jeremy L. Barth, Rupak Mukherjee, Martin J. Romeo, Silvia G. Vaena, Ge Tao, Robin C. Muise‐Helmericks, Paula S. Ramos, Russell A. Norris, Andy Wessels
Topics & Concepts
SOX9Heart developmentBiologyContext (archaeology)Mitral valvePhenotypeTranscription factorGeneCell biologyInternal medicineMedicineGeneticsEmbryonic stem cellPaleontologyCongenital heart defects researchCardiac Valve Diseases and TreatmentsCancer-related molecular mechanisms research