Construction of a copper nanocluster/MnO<sub>2</sub> nanosheet-based fluorescent platform for butyrylcholinesterase activity detection and anti-Alzheimer's drug screening
Sihan Chen, Zheng Li, Zhenzhen Huang, Qiong Jia
Abstract
. This sensing method is able to detect BChE in human serum samples and identify the serums of normal persons and cirrhotic patients effectively, indicating its great potential in the clinical diagnosis of liver diseases. Furthermore, the approach can also be used to screen BChE inhibitors, which are promising medications to alleviate the symptoms of Alzheimer's disease.
Topics & Concepts
NanosheetButyrylcholinesteraseFluorescenceCopperMaterials scienceDrugNanotechnologyChemistryPharmacologyBiochemistryMetallurgyEnzymeMedicineAcetylcholinesteraseAchéPhysicsQuantum mechanicsNanocluster Synthesis and ApplicationsCholinesterase and Neurodegenerative DiseasesCarbon and Quantum Dots Applications