<scp>l</scp> -Carnosine loaded on carboxymethyl cellulose hydrogels for promoting wound healing
Wei Zhang, Xinyi Li, Xinyi Li, Wenjian Chen, Xiaoyi Huang, Tianfeng Hua, Jinpeng Hu, Jing Zhu, Sheng Ye, Xiaojing Li, Xiaojing Li
Abstract
experiments confirmed that CRN@hydrogel can release over 80% of the drug within 48 h and demonstrated its favorable cytocompatibility and blood compatibility, thus establishing its applicability for safe utilization in clinical practice. Using a rat model, we found that this hydrogel could promote and accelerate wound healing more effectively. These results indicate that the novel hydrogel can serve as an efficient therapeutic strategy for wound treatment.
Topics & Concepts
Carboxymethyl celluloseWound healingSelf-healing hydrogelsCarnosineChemistryCelluloseSelf-healingBiochemistryPolymer chemistryOrganic chemistryMedicineSurgerySodiumAlternative medicinePathologyBiochemical effects in animalsWound Healing and TreatmentsBee Products Chemical Analysis