Myricetin prevents high molecular weight Aβ1-42 oligomer-induced neurotoxicity through antioxidant effects in cell membranes and mitochondria
Atsushi Kimura, Mayumi Tsuji, Taro Yasumoto, Yukiko Mori, Tatsunori Oguchi, Yuya Tsuji, M Umino, Asami Umino, Toru Nishikawa, Shiro Nakamura, Tomio Inoue, Yuji Kiuchi, Masahito Yamada, David B. Teplow, Kenjiro Ono
Topics & Concepts
MyricetinOxidative stressChemistryMitochondrionReactive oxygen speciesInner mitochondrial membraneLipid peroxidationNeurotoxicityMitochondrial ROSBiochemistryMitochondrial permeability transition poreCell biologyAntioxidantProgrammed cell deathBiologyApoptosisToxicityQuercetinKaempferolOrganic chemistryAlzheimer's disease research and treatmentsCholinesterase and Neurodegenerative DiseasesMedicinal Plants and Neuroprotection