Impact of Pneumococcal and Viral Pneumonia on the Respiratory and Intestinal Tract Microbiomes of Mice
Laurin Christopher Gierse, Alexander Meene, Sebastian B. Skorka, Fabian Cuypers, Surabhi Surabhi, Borja Ferrero‐Bordera, Bernd Kreikemeyer, Dörte Becher, Sven Hammerschmidt, Nikolai Siemens, Tim Urich, Katharina Riedel
Abstract
Pneumonia is one of the leading causes of death worldwide. Here, we compared the impact of bacterial- and viral-induced pneumonia on the respiratory and gastrointestinal microbiome. Using a meta-omics approach, we identified specific profiles that allow discrimination between bacterial and viral causative.
Topics & Concepts
PneumoniaMicrobiomeRespiratory tractViral pneumoniaPneumococcal pneumoniaImmunologyRespiratory systemRespiratory tract infectionsBiologyStreptococcus pneumoniaeVirologyMicrobiologyMedicineCoronavirus disease 2019 (COVID-19)Internal medicineAntibioticsBioinformaticsInfectious disease (medical specialty)DiseasePneumonia and Respiratory InfectionsViral gastroenteritis research and epidemiologyRespiratory viral infections research