Synthesis of novel pyrroles and fused pyrroles as antifungal and antibacterial agents
Rania H. Abd El‐Hameed, Amira I. Sayed, Shima Mahmoud Ali, Mohamed A. Mosa, Zainab M. Khoder, Samar S. Fatahala
Abstract
gave the best anti-phytopathogenic effect at a 50-fold lower concentration than Kocide 2000, introducing a safe commercial candidate for agricultural use. The effect of the compounds on DNA was monitored to detect the mode of action.
Topics & Concepts
AntimicrobialBacteriaCandida albicansAntifungalMode of actionMicrobiologyCombinatorial chemistryChemistryAntibioticsAntibacterial activityStereochemistryBiologyBiochemistryGeneticsSynthesis and Characterization of PyrrolesSynthesis and biological activitySynthesis and Biological Evaluation