(2R,6R)-hydroxynorketamine improves PTSD-associated behaviors and structural plasticity via modulating BDNF-mTOR signaling in the nucleus accumbens
Luping Gou, Yu Li, Shiqi Liu, Haohan Sang, Jiajun Lan, Jin-Hong Chen, Ling Wang, Changjiang Li, Bo Lian, Xianqiang Zhang, Hongwei Sun, Lin Sun
Topics & Concepts
Nucleus accumbensSynaptic plasticityNeurosciencePI3K/AKT/mTOR pathwayBrain-derived neurotrophic factorNeurotrophic factorsPsychologyLong-term potentiationNeuroplasticityInternal medicineEndocrinologyMedicineSignal transductionBiologyCell biologyReceptorCentral nervous systemNerve injury and regenerationMemory and Neural MechanismsPosttraumatic Stress Disorder Research